The analysis was carried out as part of experimentation with design-led territorial and digital tools in the Horizon Europe project Democratising jUst Sustainability Transitions (DUST) in Norrbotten (SE), Stara Zagora (BG), Katowice (PL), and Lusatia (DE)
doi: 10.1038/nature01036 65 Colunga BiancatelliRMLBerrillMCatravasJDet al
The pathophysiology of DDES is complex, involving lacrimal gland mitochondrial dysfunction, neuro-inflammation, ocular surface dysbiosis, and meibomian gland dropout [122,123,124]
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Both mechanisms increase cytoplasmic concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), producing a cytoplasmic surge of monoamines